有机化学，化学生物学，博士，副教授

电话：86-0315-3863122   传真：86-0315-3863122

电子信箱：128064@tstc.edu.cn

2001-2005 唐山师范学院化学系 获理学学士学位  

2005-2008 浙江师范大学化学与生命科学学院   获理学硕士学位

2013-2016 北京师范大学化学学院获理学博士学位

2016-2019西北工业大学生命学院 讲师

2019- 唐山师范学院化学系 讲师   副教授

主讲课程：

有机化学、无机及分析化学、有机化学实验、基础化学实验

研究领域和兴趣：非病毒药物载体、荧光探针

主要研究领域为多功能核酸药物载体和荧光探针。内容涉及到多功能核酸药物载体和荧光探针分子设计、合成、结构及性质研究，特别是含大环多胺的基因载体及荧光探针性质的研究，以及它们在重大疾病诊断和治疗中的应用。

代表性论文和专著：

1.        Yongguang Gao*, Xinhua Liu, Na Chen,   Xiaochun Yang and Fang Tang, Recent Advance of Liposome Nanoparticles for   Nucleic Acid Therapy. Pharmaceutics, 2023, 15, 178.

2.        Yongguang Gao*, Zhanda Fu, Junxia Guan,   Xinhua Liu and Qing Zhang*, The role of Notch signaling pathway in metabolic   bone diseases. Biochemical Pharmacology，2023, 207,   115377.

3.        Yongguang Gao*, Na Chen, Zhanda Fu and Qing   Zhang*, Progress of Wnt Signaling Pathway in Osteoporosis. Biomolecules 2023,   13, 483.

4.            Jingxian Jia, Yongguang Gao*, Kai Dang, Xiaosong Guo and   Aixiang Ding*, Naphthalimide-modified dendrimers as efficient and low cytotoxic   nucleic acid delivery vectors. Polymer International, 2021, 70,   1590–1594.

5.        高永光*, 贾静娴, 王丽红, 张红霞, 陈伟, 罗丹明B 修饰的树枝状分子作为核酸递送载体的研究. 化学通报. 2021, 84(8), 829-834.

6.           Yongguang Gao*, Suryaji Patil, and Jingxian   Jia, The Development of Molecular Biology of Osteoporosis. International   Journal of Molecular Sciences, 2021, 22, 8182.

7.           Yongguang Gao，Suryaji Patil and Airong   Qian*. The Role of MicroRNAs in Bone Metabolism and Disease. International Journal   of Molecular Sciences, 2020, 21, 6081.

8.           Yong-Guang Gao*, Shu-Yuan Huangfu,   Suryaji Patil, Quan Tang, Wan Sun, Yu L, Zhong-Lin Lu* and Ai-Rong Qian*.   [12]aneN₃-based multifunctional compounds as fluorescent probes   and nucleic acids delivering agents. Drug Delivery, 2020, 27, 66-80.

9.           Yongguang Gao, Kai Dang, Wen-Juan Zhang,   Fen-Li Liu, Suryaji Patil, Abdul Qadir, Ai-Xiang Ding and Ai-Rong Qian. A   1,8-naphthalimide-[12]aneN₃ derivative for efficient Cu²⁺   recognition, lysosome staining and siRNA delivery. Colloids and Surfaces   B: Biointerfaces. 2019, 185, 110607.

10.       Yongguang Gao, Fen-Li Liu, Suryaji Patil,   Di-Jie Li, Abdul Qadir, Xiao Lin, Ye Tian, Yu Li and Ai-Rong Qian.   1,8-Naphthalimide-Based Multifunctional Compounds as Cu²⁺ Probes,   Lysosome Staining Agents, and Non-viral Vectors. Frontiers in Chemistry.   2019, 7, 616.